Eagles starter Emmet Sheehan was strong early but the Seminoles jumped on him in the fourth inning on the way to a 5-1 victory.
Boston College baseball dropped its first midweek game of the season with a 12-0 blowout loss against UConn.
Boston College baseball lost 16-12 to Clemson on Friday in an offensive, back and forth battle to start the three-game series.
The Eagles trailed 8-0 midway through the third but steadily clawed back and pulled ahead in the seventh to win 10-9.
Boston College baseball lost to UNC 5-4 on Sunday to complete a two-games-to-one series loss.