Charlotte North failed to register a point for just the second time in her BC career as Syracuse took a commanding early and won 16-7.
Jenn Medjid netted the game winner, and Rachel Hall made a clutch save in the final minute to lift Boston College lacrosse over Syracuse.
Thanks to four goals each from Belle Smith and Charlotte North, No. 5 Boston College lacrosse took down No. 4 Notre Dame on Thursday.
Charlotte North broke the single-game goal record for Boston College lacrosse on Saturday, leading the Eagles to a 21-11 win over Virginia Tech.
Louisville led 12-9 midway through the second half but BC fought back to tie the game with nine minutes to play and won 14-13 in OT.
Boston College lacrosse held No. 18 UMass scoreless for 28 minutes en route to a 19-7 victory.